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States » SouthPosted at: Jan 14 2020 8:51PM


CCMB team develops new method 'Lyse – Reseal' to make genetic alterations in malaria parasite

Hyderabad, Jan 14 (UNI) Hyderabad-based CSIR-Centre for Cellular and Molecular Biology- CSIR, have developed a novel and economic way of gene delivery within the Plasmodium falciparum cells, called ''Lyse-Reseal'' method, CCMB said in a statement here on Tuesday.
Dr Puran Singh Sijwali’s group has shown the technique to be as effective as electroporation with two different Plasmodium falciparum strains, and works with 10 times lesser DNA than what is needed in electroporation.
The main advantage of their method is that it does not require an expensive electroporation device and other proprietary accessories. Hence, it can be used for Plasmodium falciparum genetic studies even in low-resource labs, which is usually a case in the regions endemic for malaria.
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Tags: #CCMB team develops new method ''Lyse – Reseal'' to make genetic alterations in malaria parasite
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