Thursday, May 24 2018 | Time 08:08 Hrs(IST)
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  • Bank of Korea chief says decision to keep rates steady was unanimous
  • U S -led coalition hits Syrian army base - Hezbollah media unit
  • N Korea says future of summit with U S is up to Washington -KCNA
  • At least four dead, 15 wounded in Baghdad suicide attack
  • Shiv Sena chief targets BJP
  • Iran's top leader sets 7 conditions to remain in nuclear deal -official website
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AstraZeneca's Lynparza meets main goal in breast cancer study

UNDATED,Feb 17 (Reuters) AstraZeneca Plc said Lynparza, already approved to treat ovarian cancer, met the main goal of helping breast cancer patients live longer without their condition worsening in a late-stage study.
The drugmaker's shares were up 2.37 percent at 4,554 pence on the London Stock Exchange, while its U.S.-listed shares were up 1.70 percent at $29.25 in premarket trading on Friday.
Lynparza, which won U.S. approval for ovarian cancer in 2014 and generated 2016 sales of $218 million, is one of the drugs that the drugmaker hopes will help achieve its target of more than $40 billion in annual revenue in 2023.
The study result should further establish Lynparza's competitive profile beyond a subset of ovarian cancers with multiple other tumors and combination opportunities ahead, Morgan Stanley analysts said.
Lynparza belongs to a closely watched class of new medicines called PARP inhibitors, which block enzymes involved in repairing damaged DNA, thereby helping to kill cancer cells.
The study compared Lynparza with chemotherapy in patients with BRCA-mutated metastatic breast cancer and is the first positive trial to evaluate the efficacy and safety of a PARP inhibitor beyond ovarian cancer, the British drugmaker said.
The trial results represent a win for AstraZeneca as well as providing the first validation for the PARP inhibitor class outside of ovarian cancer, Leerink Partners analysts wrote in a client note
REUTERS CJ AN1912
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Archbishop Philip to step down after sex abuse cover-up

Archbishop Philip to step down after sex abuse cover-up

23 May 2018 | 7:09 PM

Sydney, May 23 (UNI) A Catholic archbishop in Australia convicted of concealing child sexual abuse will step down from his position, say the BBC News report on Wednesday.

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Santa Fe school shooting: Hundreds at Sabika funeral

23 May 2018 | 6:05 PM

Karachi, May 23 (UNI) The funeral of a Pakistani student killed in last week's Texas school shooting has taken place in Karachi, according to a BBC News report on Wednesday.

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Abortion is legal in Italy — so why are women being refused?

Abortion is legal in Italy — so why are women being refused?

23 May 2018 | 6:03 PM

Rome, May 23 (UNI) Women’s abortion rights in Italy are the worst they have been since the 1970s as a civil war rages on the issue, campaigners claim according to an Euronews report.

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Xi calls for enhanced security cooperation among SCO members

Xi calls for enhanced security cooperation among SCO members

23 May 2018 | 5:54 PM

Beijing, May 23 (UNI) The Shanghai Cooperation Organisation (SCO), with the entry of India and Pakistan into the grouping, has gained more potential for security cooperation, Chinese President Xi Jinping has said.

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Belarus says same-sex relationships are 'fake'

23 May 2018 | 4:28 PM

Minsk, May 23 (UNI) The Belarusian government has called same-sex relationships "fake" after blasting the UK embassy in Minsk for displaying a rainbow flag on the International Day Against Homophobia, Transphobia and Biphobia (IDAHOT).

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